Anticoagulation

Learning Objectives:

• Read, understand, and apply AcForum 2016 guidelines, CHEST 2012 guidelines, and CHEST 2016 VTE update to perform the following:
  • Assess a patient case and recommend optimal anticoagulation treatment and duration for:
    • atrial fibrillation
    • bioprosthetic and mechanical heart valve replacement
    • provoked, unprovoked, cancer associated, non-cancer associated venous thromboembolism
  • Assess a patient case and recommend optimal perioperative management of anticoagulation for:
    • atrial fibrillation
    • bioprosthetic and mechanical heart valve replacement
    • provoked, unprovoked, cancer associated, non-cancer associated venous thromboembolism

Online Module
Review of the following guidelines is recommended prior to beginning the module questions:

2012 CHEST guidelines:

• Oral Anticoagulant Therapy, Ageno W, Gallus AS, Wittkowsky A, Crowther M, Hylek EM, Palareti G. Chest. 2012;141(2_suppl):e44S-e88S. doi:10.1378/chest.11-2292.
  Evidence-Based Management Of Anticoagulant Therapy, Holbrook A, Schulman S, Witt DM, et al. Chest. 2012;141(2_suppl):e152S-e184S. doi:10.1378/chest.11-2295.
  Perioperative Management Of Antithrombotic Therapy, Douketis JD, Spyropoulos AC, Spencer FA, et al., Chest. 2012;141(2_suppl):e326S-e350S. doi:10.1378/chest.11-2298.
  Antithrombotic Therapy For Atrial Fibrillation, You JJ, Singer DE, Howard PA, et al. Chest. 2012;141(2_suppl):e531S-e575S. doi:10.1378/chest.11-2304.
  Antithrombotic And Thrombolytic Therapy For Valvular Disease, Whitlock RP, Sun JC, Fremes SE, Rubens FD, Teoh KH. Chest. 2012;141(2_suppl):e576S-e600S. doi:10.1378/chest.11-2305.

2016 CHEST VTE update:

• Antithrombotic Therapy For Vte Disease: Chest Guideline And Expert Panel Report, Kearon C, Akl EA, Ornelas J, et al. Chest. 2016;149(2):315-352.doi:10.1016/j.chest.2015.11.026

2016 Management of Venous Thromboembolism: Clinical Guidance from the Anticoagulation Forum

• Guidance for the prevention and treatment of cancer-associated venous thromboembolism Khorana, A.A., Carrier, M., Garcia, D.A. et al. J Thromb Thrombolysis (2016) 41: 81. doi:10.1007/s11239-015-1313-4